Paris-Saclay Institute of Neuroscience
Neuronal Circuits and Motor Control
Head: Julien Bouvier
Experimentation
From physiology, behavior, histology, imaging, to cutting-edge microscopy and data-analysis, we are kept busy while always experimenting new exciting methodological evenues!
Viral injections in a fully-equipped BSL2 laboratory are used to deliver various neuronal actuators (e.g. opsins, DREADDs, GCaMPs) and retrograde and anterograde tracing tools.
Data analysis requires various skills interfacing programming, statistics and use of deep learning-based tracking.
Fonctional investigations include: in vivo optogenetics and calcium-imaging, electromyographic recordings and various motor tests (open-field, treadmill, catwalk,...).
Our work also has a strong use of histology techniques, including vibratome and cryostat sectionning, immunohistochemistry on tissue sections but also whole-brain clearing techniques.
We utilize a variety of microscopes, including epifluorescent, confocal and light-sheet microscopes to characterize and reconstruct labelled cells and circuits.
Seminars & congresses
Lab members are actively engaged in participating to local and international meetings, presenting their work on posters or with talks.
Poster presentation at the "Neuro-PSI Talents Day" 2019
Coralie presents at the "Neuro-PSI T@lents day", and wins the "most motivated" prize !
Poster presentation at NeuroFrance 2019
Refreshments in Marseille during NeuroFrance 2019
