Paris-Saclay Institute of Neuroscience
Neuronal Circuits and Motor Control
Head: Julien Bouvier
Experimentation
From physiology, behavior, histology, imaging, to cutting-edge microscopy and data-analysis, we are kept busy while always experimenting new exciting methodological evenues!
A fully-equipped BSL2 laboratory is used to deliver various neuronal actuators and tracing tools.
Electrophysiology is used to record, image and interfere with neuronal activity in vitro.
Fonctional investigations include: in vivo optogenetics and calcium-imaging, electromyographic recordings and various motor tests (open-field, treadmill, catwalk,...)
Our work also has a strong use of histology techniques, including vibratome and cryostat sectionning, immunohistochemistry on tissue sections but also whole-brain clearing techniques.
Data analysis requires various skills interfacing programming, statistics, computer vision, and deep learning-based tracking.
We utilize a variety of microscopes, including epifluorescent, confocal and light-sheet microscopes to characterize and reconstruct labelled cells and circuits.
Seminars & congresses
Lab members are actively participating in local and international meetings, presenting their work on posters or with talks.
Lab meetings & social events
We meet weekly for discussing ongoing work, brainstorming ideas, practicing talks and for reviewing litterature. We also organize one or two "team-building" days per year, where science meets with fun!
